Flaxseed influences the metabolism of female estrogen. 18 menopausal female subjects were asked to consume 10g of flaxseed daily for 4 months. As a result, the luteal phase menstrual cycle was lengthened. On the other hand, 25 menopause female subjects were asked to consume 25g of flaxseed every day and as a result, the flaxseed stimulated the virginal cell maturation which confirmed that flaxseed has effects on estrogen in the female reproductive organs. Moreover, after ingesting 40g of flaxseed for 4 months, 25 menopausal women suffering from menopausal symptoms were relieved from the symptoms and show similar results of those undergoing hormone replacement therapy (taking 0.625mg of synthetic estrogen).